Permethrin

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Product Information

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Medically Verified
Dr.J Vázquez | Expert Transtoyou

Dr. J. Vázquez

General Medicine Doctor | REG: 282889782

Reviewed on: 15 June, 2025 View Profile

Dr. Josefina Vázquez is an experienced physician with over three years in emergency medicine, reanimation, and specialized transport.

Description

Permethrin is a topical medication formulated to treat scabies. a highly contagious skin infestation caused by the mite Sarcoptes scabiei. It spreads primarily through prolonged skin-to-skin contact and is associated with intense itching (especially at night) and a red, bumpy rash in areas such as the fingers, wrists, elbows, and groin.

Permethrin belongs to the synthetic pyrethroid class and works by disrupting the sodium channels in the nervous system of mites, leading to paralysis and death. It targets both adult mites and their eggs, helping eliminate the infestation and reduce inflammation caused by the immune response to the mites.

The cream is applied to clean, dry skin from the neck down, including between fingers/toes, under nails, and around skin folds (e.g., wrists, buttocks, genitals). The cream should be left on the skin for 8 to 14 hours, then thoroughly washed off. A second application may be needed after 7 to 14 days under medical supervision if symptoms persist.

Post-treatment itching is common and may persist for several weeks even after successful mite eradication. This is part of the body’s immune response and does not necessarily indicate treatment failure.

Permethrin is safe and well-tolerated in most patients. Mild side effects such as redness, stinging, or temporary itching may occur and usually resolve without intervention.

General Information

What is [Product name]?

A topical antiparasitic used primarily for scabies and lice. It is available as a cream (5%) for scabies and lotion (1%) for lice. 

What is [Product name] used for?

Primarily scabies treatment; also prescribed for head and pubic lice infestations, depending on the formulation. 

How does [Product name] work in the body?

It disrupts nerve function in mites and lice by altering sodium transport across their membranes, causing paralysis and death. 

What is the general recommended dosage for [Product name]?

Apply once and leave on for 8–14 hours. A second application may be necessary after 7–14 days depending on symptoms and reinfestation risk. 

How long does it take to feel the effects of [Product name]?

Permethrin starts working immediately. Itching may persist for up to 2–4 weeks after treatment due to allergic reactions to dead mites. 

What should I do if I forget a dose?

Apply as soon as you remember and leave on for the full treatment window before rinsing. Do not shorten application time. 

Safety & Side Effects

What are the possible side effects of [Product name]?
  • Common: redness, itching, tingling, or mild burning. These are typically short-lived and do not require stopping treatment.
  • Rare: contact dermatitis or allergic reactions. Discontinue and consult a doctor if symptoms worsen. 
What are the contraindications of [Product name]?

Do not use if allergic to permethrin, pyrethrins, or any component of the cream. Avoid use on inflamed, broken, or extensively damaged skin. 

Can I combine [Product name] with other medications?

Generally safe, but avoid using other skin treatments (e.g., steroids, emollients) on the same area during treatment unless directed by your provider. 

Can I use this if I am pregnant or breastfeeding?

Yes , Permethrin is generally considered safe (pregnancy category B). However, consult your healthcare provider before use during pregnancy or breastfeeding. 

Is it safe to drink alcohol while using [Product name]?

Yes. There are no known interactions between alcohol and topical Permethrin. 

Usage & Administration

How do I administer [Product name]?

Massage cream into the entire body surface, including under nails and between skin folds. Do not apply to eyes or mouth. 

How should I store [Product name] properly?

Store at room temperature in a dry place. Keep tightly closed and out of reach of children. 

Should I take [Product name] with food?

Not applicable because this is a topical cream, not taken orally. 

Can I crush or dissolve the tablet in water?

Permethrin is not available in tablet form for scabies. Use only as a topical cream as directed. 

Ordering & Delivery

How can I order [Product name] online?

To get [Product name], fill out a medical form or book a video consult with a doctor via Transtoyou. After approval, your prescription is sent to the pharmacy for fast delivery.

Do I need a prescription for [Product name]?

[Product name] requires a valid prescription, which is issued after the doctor reviewed your answered in the medical questionnaire or via a video consultation with the doctor.

How fast is [Product name] delivered?

After approval by a doctor from Transtoyou, the prescription of [Product name] is forwarded to an affiliated pharmacy and typically shipped within 1–2 working days.

Can I return [Product name] if I change my mind?

For safety and legal reasons prescription medication (RX) and in this case [Product name] is non-returnable once shipped. 

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Permethrin

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